Bisphosphonates breast cancer

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Evidence summary [ES15] Published date: July Bisphosphonates are commonly used in patients with breast cancer to reduce skeletal-related events in metastatic disease and to mitigate bone loss associated with adjuvant therapy.Bisphosphonates can reduce the rate of breast cancer recurrence in bone, according to a meta-analysis of randomized trials of bisphosphonates as adjuvant therapy for women with early-stage breast cancer.Study record managers: refer to the Data Element Definitions if submitting registration or results information.Clinical trials are investigating the use of bisphosphonates in patients with early nonmetastatic breast cancer.Opinion statement Bisphosphonates are utilized routinely in breast cancer.

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Bisphosphonates are the most commonly prescribed and most effective class of drugs for the treatment of osteoporosis.Among 3, patients randomized to adjuvant bisphosphonate therapy following chemotherapy, there was barely a speck of difference in either disease-free survival DFS or overall survival OS between patients randomized to either 2 years or 5 years of adjuvant bisphosphonate therapy with zoledronate, reported Wolfgang Janni, MDfrom University Hospital Ulm Germany.By Ruth M.

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